National Instruments provides a wide array of data acquisition hardware for use in many platforms, operating systems, and busses. The most common way provided to interface with the hardware is through the NI-DAQmx drivers. These DAQmx drivers can be used to interface with hundreds of different DAQ devices across several different application development platforms. In this three part blog series, we are going to explore specifically how to use National Instruments data acquisition hardware in .NET applications. Part one will introduce a little bit of background into DAQmx and Measurement Studio. Part two will explain how to get started in adding National Instruments hardware to your .NET project. Finally, part three will provide some examples for hybrid systems combining LabVIEW and .NET as a way to fully utilize National Instruments hardware while retaining the advantages of .NET.